CardioDec 1, 2025 4 min read

Omega-3 (EPA/DHA) and Blood Triglyceride Management

Omega-3 EPA/DHA is a leading ingredient recognized for blood triglyceride management. Here are the mechanism, form characteristics, and oxidative stability essentials.

Omega-3 is an unsaturated fatty acid abundant in oily fish, and steady supplement demand exists because diet alone often falls short. EPA and DHA in particular are leading functional ingredients recognized for blood triglyceride management.

Omega-3 Ingredient Overview

Omega-3 raw materials differ by their bound form.

TG (triglyceride) form: Close to the natural form.
EE (ethyl ester) form: Easy to concentrate for higher content.
rTG (re-esterified TG) form: EE converted back to TG, aiming for high concentration and absorption.

Sources are typically small fish such as anchovy and sardine, while algae-derived DHA serves plant-based positioning.

Mechanism (Research Perspective)

EPA/DHA are reported to act on lipid synthesis pathways in the liver, helping maintain blood triglyceride levels. EFSA assessed that EPA/DHA contribute to maintaining normal blood triglycerides under defined intake conditions, and NIH ODS summarizes related research.

Schematic showing EPA/DHA acting on triglyceride synthesis pathways in the liver to help maintain blood triglyceride levels

Dosing, Content, and Specification

Because omega-3 is prone to oxidation, quality control is especially important.

Clearly design and label total EPA+DHA content and ratio
Manage rancidity indices (peroxide value, anisidine value, TOTOX)
Verify purification levels for heavy metals and pollutants

Key takeaway: Omega-3 is a blood triglyceride management ingredient; form (TG/EE/rTG) and oxidative stability determine product credibility.

OEM Formulation Considerations

Standardization and stability design are central to omega-3 product quality.

Standardization: EPA/DHA content specs and CoA
Sourcing: Fish vs. algae origin and sustainability certifications (e.g., MSC)
Antioxidation: Tocopherol treatment, nitrogen flushing, light-blocking packaging
Formulation: Coating and flavor masking to reduce fishy odor

Keep claims within approved scope and avoid statements implying disease treatment.

Ingredient Inquiry

For omega-3 specifications by form and concentration, compare in our [ingredient catalog](/catalog), or request a quote via [RFQ](/rfq).

#오메가3#EPA DHA#중성지질#혈중 지질#건강기능식품 원료

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Frequently asked questions

What is the difference between TG and rTG omega-3?

TG is close to the natural form, while rTG re-converts ethyl ester back to TG to combine high concentration with absorption. Choose based on content targets, cost, and absorption concept.

How is omega-3 oxidation verified?

Rancidity is assessed via peroxide value, anisidine value, and the combined TOTOX index. Checking these with the CoA at intake is recommended.

Can blood triglyceride functionality be claimed?

EPA/DHA-containing oils are recognized in Korea for triglyceride-related functionality. However, content thresholds must be met and claims must stay within the approved scope.

References

This content is for informational purposes only and does not guarantee the prevention or treatment of any disease. It references the following authoritative sources.